Figure 4.
Platelet counts over the course of treatment for those who developed neutralizing antibodies. Horizontal dashed line indicates threshold for platelet response (50 × 109/L). Arrows indicate visits at which the patient tested positive for neutralizing antibodies. For patients who had transient neutralizing antibodies (ie, patients 1, 2, 5, and 6), the gray boxes denote indicative periods for which the patients were positive for neutralizing antibodies, and vertical dashed lines indicate visits when the patient no longer tested positive. ∗Patient 5 had multiple positive-to-negative and negative-to-positive visits; only the duration of the first positive-to-negative result is shown.

Platelet counts over the course of treatment for those who developed neutralizing antibodies. Horizontal dashed line indicates threshold for platelet response (50 × 109/L). Arrows indicate visits at which the patient tested positive for neutralizing antibodies. For patients who had transient neutralizing antibodies (ie, patients 1, 2, 5, and 6), the gray boxes denote indicative periods for which the patients were positive for neutralizing antibodies, and vertical dashed lines indicate visits when the patient no longer tested positive. ∗Patient 5 had multiple positive-to-negative and negative-to-positive visits; only the duration of the first positive-to-negative result is shown.

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