Figure 3.
Effect of FXII deficiency on mouse TG in WB and PPP. TG in both WB and PPP of F12+/+ control mice and F12−/− mice were triggered by 120× diluted silica or 0.05/0.5 pM TF and recalcification (4 μM phospholipids were added in PPP). Representative curves of (A) WB- and (E) PPP-TG. Bar graphs of lag time (B,F), peak height (C,G), and ETP (D,H) are shown as median (n = 5 mice per group). Comparisons between groups were made using the Mann-Whitney test. ∗P < .05; ∗∗P < .01.