Correlation between titers of apparent oligoreactive FVIII- and FIX-binding antibodies in HIPS-ITI patient 2 during HIPS-ITI. (A-B) Correlation analyses between apparent oligoreactive FVIII-binding IgG1 respectively IgG2 titers and FIX-binding total Ig (A) as well as apparent oligoreactive FVIII-binding IgA and FIX-binding total Ig (B) during HIPS-ITI (ED70 to ED388) of HIPS-ITI patient 2. Spearman correlation coefficients (r) with 95% CIs (given in brackets) are presented in the figure legends. Statistically significant correlations are highlighted, ∗P ≤ .05 and ∗∗P ≤ .01.