Figure 3.
Identification of circulating KIV during KSHV-MCD flare using LNA/vIL-6 flow-FISH. Flow-FISH was performed on the peripheral blood of 6 patients with confirmed KSHV-MCD flare. LNA+ and/or vIL-6+ cells are represented among CD3+ (T cells), CD14+ (monocytes), and CD3−CD14− cells. Values are given as percentages of positive cells among CD3−CD14− cells. LNA+ and/or vIL-6+ cells are depicted in red in an IgM/CD38 dot plot for each patient, showing that most of the infected cells are IgM+ and CD38+ cells.