Figure 5.
hIL-6 and hIL-10 intracellular staining on PBMCs from 3 patients with KSHV-MCD flare. PBMCs were left unstimulated and intracellular detection of hIL-6 (top) and hIL-10 (bottom) was assessed in KIV, T cells, B cells, and monocytes. KIV staining is shown for the 3 patients (P1, P3, and P7), whereas staining of T cells, B cells, and monocytes is only shown for 1 representative patient (P1) for the purpose of clarity. hIL-6 and hIL-10 staining was negative in B cells and T cells from the 3 patients tested, whereas P3 and P7 had 15% and 47%, respectively, IL-6+ monocytes.