Figure 1.
Anti-CMV T-cell activity and clinical response in patients treated with CMV-specific VSTs for active CMV infection. (A) Anti-CMV antigen (phosphoprotein 65 [PP65], immediate early protein-1 [IE1]) T-cell response of the CMV-specific VST products as detected by IFN-γ ELISpot assay. Anti-CMV antigen T-cell response and CMV viral load (IU or copies per milliliter) in the recipient PB post-VST infusion for patient P4, P5, P7 treated with CMV infection (B-D) and timing of concomitant standard antiviral treatment. PCR, polymerase chain reaction; SFU, spot forming units.