C1INH deficiency does not enhance arterial thrombosis in mice. Arterial thrombosis was assessed in C1inh^+/+, C1inh^+/−, and C1inh^−/− mice using the carotid artery FeCl₃ model under conditions resulting in either severe or mild injury. In the severe model induced with application of 8% FeCl₃ for 3 minutes, (A) occlusion time and (B) carotid artery patency were evaluated. Similarly, in the mild model induced with application of 2.5% FeCl₃ for 5 minutes, (C) occlusion time and (D) carotid artery patency were evaluated. Data are represented as individual values with median and analyzed using Kruskal-Wallis with post hoc Dunn or log-rank tests.