Figure 1.
TET2 truncating mutation is associated with poor overall survival. Kaplan-Meier curves depicting 57 patients, including 5 patients with BPDCN and other myeloid neoplasms in the same bone marrow. (A) Overall survival of the cohort with censoring based on the final follow-up or death based on the type of TET2 mutation (B) Overall survival of the cohort with censoring based on time to stem cell transplant or based on the type of TET2 mutation (C) Overall survival of the cohort with censoring based on the final follow-up or death based on the number of TET2 mutations per patient, regardless of the mutation type. wt, wild-type; ms, missense; ns, nonsense; fs, frameshift; splice, splice site. Cox proportional HRs and P values are shown for each curve.