Trajectoryof all%FEV1 measurements collected while on belumosudil therapy. Graphical representation demonstrates the %FEV1 measurements for subjects who were responders (PR or CR by NIH criteria, n = 19) in red and nonresponders (n = 40) in gray. Fitted lines for responders and nonresponders generated using locally weighted smoothing (LOESS technique) to visually present the relationship between %FEV1 and response over time.