Figure 4.
Ifnar1 deletion does not impair lymphopoiesis or mature blood production. (A-D) Absolute numbers of indicated B-cell progenitor populations in P0 liver or P14 bone marrow from mice of Ifnar1+/− and Ifnar1–/–-mice, or spleen B-cell populations from the same mice. (E-H) Absolute numbers of thymocyte subpopulations Ifnar1+/− and Ifnar1–/–-mice, or spleen T-cell populations from the same mice. (I-L) White blood cell (H), absolute neutrophil (I), red blood cell (J), and platelet (K) counts presented for 1 μL of blood from P14 mice. For all panels, n = 4 to 11 and error bars reflect standard deviation. Surface marker phenotypes are specified in supplemental Table 2, and gating strategies are shown in supplemental Figure 5. Comparisons performed using two-tailed t test did not show significant differences between Ifnar1+/− and Ifnar1–/–-mice for any measurement.

Ifnar1 deletion does not impair lymphopoiesis or mature blood production. (A-D) Absolute numbers of indicated B-cell progenitor populations in P0 liver or P14 bone marrow from mice of Ifnar1+/− and Ifnar1–/–-mice, or spleen B-cell populations from the same mice. (E-H) Absolute numbers of thymocyte subpopulations Ifnar1+/− and Ifnar1–/–-mice, or spleen T-cell populations from the same mice. (I-L) White blood cell (H), absolute neutrophil (I), red blood cell (J), and platelet (K) counts presented for 1 μL of blood from P14 mice. For all panels, n = 4 to 11 and error bars reflect standard deviation. Surface marker phenotypes are specified in supplemental Table 2, and gating strategies are shown in supplemental Figure 5. Comparisons performed using two-tailed t test did not show significant differences between Ifnar1+/− and Ifnar1–/–-mice for any measurement.

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