Evaluation of the BCA and cytokine profile and clinical outcome of the patients. (A) The kinetics of circulating CD19⁺ cells was monitored via flow cytometry over time in the peripheral blood of all the treated patients. (B) The levels of interferon gamma (IFNg), interleukin-10 (IL-10), IL-6, and tumor necrosis factor α (TNFa) were measured in the plasma of patients after infusion, and the concentrations at peak are shown. (C) Flowchart summarizing the responses and relapses observed in the cohort of patients; (D) Swimmer plot of all the treated patients showing the disease outcome and the patients receiving allo-HSCT. CR, complete remission; OS, overall survival.