Figure 1.
Gut microbiota alpha diversity of patients with PV, of the different PV treatment groups, and of HCs. (A) Gut microbiota alpha diversity (median Inverse Simpson Index [InvSimpson]) of HCs and patients with PV. Alpha diversity differed significantly between patients with PV (median InvSimpson, 20.2) and HCs (median InvSimpson, 26.3) (P = .016). (B) Alpha diversity (InvSimpson) of HCs, COMBI, HU, IFN-α2, and NT group. After adjusting for multiple testing, no significant difference was found.