Coefficient estimates of factors associated with neutrophil and platelet count using a generalized linear mixed model. (A) Coefficient estimates of factors associated with neutrophil count with multivariable analysis. The horizontal axis represents coefficient estimates values and the factors are included in the vertical axis. Coefficient estimates represent the expected change in neutrophil count per 1 unit increase in factor (continuous variable such as age) or in the presence of factor (categorical variable such as smoking). (B) Plot depicting the interaction effect of age and variant rs60134943 (GSDMA) on the neutrophil count. Age is represented on the horizontal axis and the logarithm of neutrophil count is represented on the vertical axis. (C) Coefficient estimates of factors associated with platelet count. The horizontal axis represents coefficient estimate values and the factors are included in the vertical axis. Coefficient estimates represent the expected change in platelet count per 1 unit increase in factor (continuous variable, such as age) or in the presence of factor (categorical variable, such as cancer). ∗ P < .05; ∗∗ P < .01; ∗∗∗ P < .001.