Genetic landscape of SMZL-T. (A) CN profile of 27 cases of SMZL-T. On the x-axis, the chromosomes are represented horizontally from 1 to X (chromosome Y is excluded); on the y-axis, the percentages of patients with CNAs are shown, with gains depicted in blue and losses in red. Regions with an incidence of ≥4 cases and potential target genes are indicated. (B) Oncoprint displaying the recurrent alterations (n ≥ 3) found in 32 SMZL-T cases. Each column corresponds to an individual SMZL-T sample. All alterations are displayed by decreasing frequency. In the upper panel, SNVs and indels are shown in gray, deletions in red, and BCL6 translocation in green. In the lower panel, gains (blue), losses (red), and CN-LOH (yellow) of large and focal regions (potential target genes are indicated) are shown.