Summary of HRQoL overall scores by vulnerability subgroup among and disease subgroup. Number of participants (N) in each disease and vulnerability: vulnerable MDS (N = 84), MDS/MPN (N = 18), ICUS (N = 12), AML<30% (N = 5), at-risk (N = 30), nonvulnerable MDS (N = 164), MDS/MPN (N = 22), ICUS (N = 36), AML<30% (N = 10), at-risk (N = 68). Estimates based on ANCOVA model adjusted for age. P values for pairwise comparisons adjusted using the Hochberg procedure. Vulnerable defined as VES-13 ≥ 3.