Classifier performance on various combinations of clinical factors and selected cellular, plasma cytokines/chemokines, and metabolomics markers. (A) Separately adding 1 data type (cellular markers, plasma cytokines/chemokines, or metabolomics) to clinical factors. (B) Combining multiple data types. + indicates the data types used for building the classifier. Average AUC, PPV, and NPV over 1000 random train-test sample splits plotted. Error bars correspond to standard deviation.