Prevalence and impact of geriatric impairment on CAR T-cell therapy outcomes. (A) Prevalence of geriatric deficits as depicted in red bar graph. (B) Kaplan-Meyer analysis of OS stratified pre–CAR T therapy cognitive impairment (no, blue line; or yes, red line). The life table is depicted below the graph. ADL, activities of daily living; CIRS-G, cumulative illness rating scale–geriatric; IADL, instrumental activities of daily living.