Figure 1.
Overview of sample submission and patient enrollment. (A) MDS study pathology review flowchart. (B) Consort diagram for final diagnosis. 1Data available to the pathologists at the time of review included peripheral blood labs and smear, bone marrow aspirate and core/clot, flow cytometry, iron stain, cytogenetics, limited local molecular reports, patient clinical history, vitamin levels, reticulocyte counts, and immunohistochemistry. 2The National MDS Study relies on additional tertiary pathology review to adjudicate disagreements for disease classification when local and centralized pathology review are discordant.
