American Society of Hematology

Figure 4.

Mice infected with SARS-CoV-2 showed subtle effects in the liver microvasculature. Mice were infected with 2.5 × 104 pfu NG-SARS-CoV-2 via IN. IVM images (original magnification ×25) of the livers of hACE2 AC70 mice not infected (A) and infected (B-C) with NG-SARS-CoV-2 showing platelets (anti-CD49b, blue) and neutrophils (anti-Ly6G, red) (day 5 after infection). Scale bars, 23 μm (left), 10 μm (middle and right). The graph represents the quantification of the area covered by platelets per FOV after IVM. Data (where applicable) are represented as mean ± SD. ns, not significant. Unpaired Student t test was performed for statistical analysis.

Mice infected with SARS-CoV-2 showed subtle effects in the liver microvasculature. Mice were infected with 2.5 × 10⁴ pfu NG-SARS-CoV-2 via IN. IVM images (original magnification ×25) of the livers of hACE2 AC70 mice not infected (A) and infected (B-C) with NG-SARS-CoV-2 showing platelets (anti-CD49b, blue) and neutrophils (anti-Ly6G, red) (day 5 after infection). Scale bars, 23 μm (left), 10 μm (middle and right). The graph represents the quantification of the area covered by platelets per FOV after IVM. Data (where applicable) are represented as mean ± SD. ns, not significant. Unpaired Student t test was performed for statistical analysis.

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