Volcano plot of the association between baseline genetic factors on the LSC17 score in the total study population (N = 504). The x-axis represents the difference between mean values of LSC17 scores in patients with or without the variable of interest. The y-axis represents the significance of the Wilcoxon test comparing the 2 groups, adjusting for multiple testing with the Benjamini-Hochberg method (dashed line corresponding to 0.05). Red and blue circles indicate cytogenetic and gene mutations variables, respectively; size is correlated with number of patients with the variable of interest. K, karyotype.