The contribution of hematopoietic and nonhematopoietic tissues to cfDNA. (A) Schematic of the contribution of donor and recipient tissue to cfDNA after alloHCT. Red and blue depict donor and recipient tissues, respectively. In the recipient, the entire hematopoietic tissue is donor derived (red). CfDNA at different time points after alloHCT is shown. cfDNA from hematopoietic tissue is red, and nonhematopoietic tissue is blue. Relative amount of cfDNA from hematopoietic cells (donor-derived) at D60 to D90 and D180 after alloHCT is shown. Servier Medical Art, provided by Servier, was used to generate Figure 1A.