The differential sensitivity of BM and cfDNA-based variant detection. (A) Correlation between VAF of leukemia-specific somatic mutations in BM and cfDNA is shown. The data points represent individual variants. The variants detected before alloHCT (red) and D60 to D90 (blue) and D180 (green) are shown. The dashed line represents the limit of detection. (B) The leukemia-specific mutations at diagnosis, D60 to D90, and D180 after alloHCT are shown for individual patients. The dashed line marks the limit of detection. VAF is presented on a logarithmic scale.