Figure 6.
Unaltered GPVI and CLEC-2 densities in neonatal platelets. Characteristics of preterm neonates <32 weeks GA, 32 to 36 weeks GA, >36 weeks GA (t), infants 28d-2a, children 2 to 13a and adults >13a are displayed. (A) GPVI and (B) CLEC-2 expression were assessed by flow cytometry. (C) GPVI or (D) CLEC-2 expression vs forward scatter (FSC) and (E) FcγRIIa expression are displayed. (F-G) CD62P expression after antibody (HY101) induced GPVI stimulation. (G) CD62P expression vs GA. All graphs show median ± 95% confidence interval. Differences were analyzed using Kruskal-Wallis-test. ∗P < .05; ∗∗P < .01; ∗∗∗P < .001; ∗∗∗∗P < .0001. ns, nonsignificant.