Treatments and responses of patients treated with venetoclax-based combinations. (A) Swimmer plot of patients receiving venetoclax-based combinations. Patients are divided into 3 groups based on having received venetoclax plus chemotherapy (top), venetoclax plus hypomethylating agents (middle), and both (bottom). Dots represent disease evaluation, and response is specified in the legend. (B) Summary of response for the overall cohort, for KMT2A-rearranged patients (top), and for patients with low (≤5% of blast), intermediate (5%-20% of blast), and high disease burden (≥ 20% of blast) (middle) before venetoclax start. (Bottom) The larger bar represents the response after the first cycle for patients receiving 2 or more cycles of venetoclax-based combination. The smaller bars represent the response after the second cycle for patients achieving CR, PR, and NR after the first cycle. (C) Kaplan-Meier estimates of the OS for the entire cohort (top) and patients bridged to HSCT (bottom). Rel, relapsed; Refr, refractory; Ven, venetoclax.