Analysis of possible aVWS predictors. (A) The VWF:GPIbM/vWF:Ag ratio shows the best predictability compared to the other investigated parameters. The HMWM ratio is presented in bold as test reference for aVWS diagnosis. (B) VWF:GPIbM/vWF:Ag ratio shows a significant correlation with HMWM. The red dashed lines represent the 95% prediction interval. Regression line: y = 0.4337093 + 0.4791361 × x.