Figure 3.
Multiomic analysis of single cells. Current single-cell methods can quantify numerous analytes, including scDNA-seq, messenger RNA (scRNA-seq), chromosome accessibility (assay for transposase-accessible chromatin using sequencing [scATAC-seq]), DNA methylation, intracellular proteins using mass spectrometry, and surface proteins using antibody-derived tags (ADTs). Additionally, barcoding methods coupled with both scRNA-seq and scATAC-seq can facilitate lineage-tracing studies.