The detailed data for the current study cohort. (A) The spectrum of the F9 mutations in this cohort. (B) The distribution of mutations on F9 encoding regions and FIX structure domains among 28 children with hemophilia B. Black circles represent patients with inhibitor, white circles represent non-inhibitor patients, and the number in the circle represents the number of patients. (C) The peak inhibitor titers of patients with only serine protease (SP) domain deletion and FIX truncation beyond the SP domain.