Flowchart of patient identification and distribution into respective cohorts. The entire cohort includes 132 patients with NGS of tumor samples. CCD was available for 87 patients, and 72 patients were managed by an MSK oncologist for their first-line treatment and had tumor NGS before or during CHOP-based treatment. CNS, central nervous system; CR1, first complete remission; EATL, enteropathy-associated T-cell lymphoma.