Human plasma and murine tissue biomarkers in HSCT recipients. Plasma (A) Reg3α, (B) ST2, and (C) LBP levels. (D) day +7 LBP and L:R ratios. Plasma (E) claudin1, (F) occludin, and (G) IAP levels. Representative 8× section (H) of control mouse duodenum stained for claudin1 (brown) and (I) from mouse 14 days after lethal irradiation and HSCT. (J) Positive pixel count of 3 sections from 3 mice in each group. ∗P < .05; ∗∗P < .01; ∗∗∗P < .001; ∗∗∗∗P < .0001.