Figure 7.
Evi1KI/+ mice show low platelet count and delayed leukocyte and platelet recovery from FU treatment. The peripheral blood cells of Evi1+/+ and Evi1KI/+ age- and sex-matched littermates after FU administration (Evi1+/+, n = 7 vs Evi1KI/+, n = 7). The platelet and leukocyte count recovery of Evi1KI/+ mice was slow and delayed. Platelet count rebound of Evi1KI/+ mice was milder than that of Evi1+/+ mice. Values are the mean ± SEM of each group. Threshold significance level, P = .05 (2-tailed Welch t test).