Figure 1.
Early infections from days 0 to 100 after BCMA–directed CAR T-cell therapy.Figure 1 presents early infectious events from day 0 to day 100 (n = 42) by pathogen type and individual infection. Between day 0 and day 100 after cell infusion, 26 patients (26%) experienced 42 infectious events. Bacterial infections were the most frequent infectious event (69%), whereas viral infections were less common (17%) and fungal infections were rare (3%). Overall, 13 of 42 (31%) of early infectious events were respiratory infections involving the lungs, upper respiratory tract, or sinuses. “Pneumonia NOS” represents pneumonia diagnosed via clinical and radiographic criteria and not able to be delineated as bacterial vs viral. Amongst early infections, 3/6 cases of pneumonia were "Pneumonia NOS" and 3 cases had bacterial pathogens identified on microbiologic testing. NOS, Not otherwise specified.