Sankey plots for the change in the number of geriatric impairments over time. (A) Absolute number of geriatric impairments over time. (B) Categorization of the number of geriatric impairments in 0-1 and ≥2 geriatric impairments at baseline. Of note, the cut-off was established based on the median number of geriatric impairments at baseline. The absolute number of geriatric impairments and the patients with ≥2 geriatric impairments significantly diminished over time (P < .001), as measured using a linear mixed-effect model, with the number of geriatric impairments and their 2-way interaction with time as a fixed effect and a random intercept for patients.