Examination of myocardial microvascular perfusion and function of the experimental mice in Figure 4 using echocardiography. Elevated levels of VWF and LDL decrease myocardial blood flow (MBF) (A) and global longitudinal strain (GLS) (B). (A) MBF, MBV, and β. (B) GLS, expressed as the percent change in heart muscle in the ventricle-apex axis at end-diastole. P values were by t test.