Heptad TFs at promoters and distal regulators of genes crucial for myeloid and erythroid cell development. (A) Genes associated with myeloid development. Left: k-means clustered heatmaps of TF binding intensity at promoters and distal regulatory regions. Profile plots show normalized signal for each TF in each cell type at the regions depicted in the heatmap. Right: z score normalized heatmaps of RNA-seq counts (GSE75384) for the corresponding gene in each cell type. White rows are genes with no expression values in the data set. (B) Genes associated with erythroid development. Left: k-means clustered heatmaps of TF binding intensity at promoters and distal regulatory regions. Profile plots show normalized signal for each TF in each cell type at the regions depicted in the heatmap. Right: z score normalized heatmaps of RNA-seq counts (GSE75384) for the corresponding gene in each cell type.