Figure 2.
EFS and OS in patients in CR/CRi following tisagenlecleucel by Kaplan-Meier analyses with log-rank test P values. (A-B) EFS (A) and OS (B) of responding patients based on detection at 28 days after CAR infusion of BM NGS-MRD at any level (blue lines) compared with patients with BM NGS-MRD = 0 (green lines). (C-D) EFS (C) and OS (D) of responding patients based on detection at 3 months after CAR infusion of BM NGS-MRD at any level (blue lines) compared with patients with BM NGS-MRD = 0 (green lines). CRi, complete remission with incomplete count recovery. Reproduced with permission from CCC Marketplace, license number 1257504-1, from Pulsipher et al.36