Total MPM and a number of specific taxa are elevated in samples from patients after transplantation. (A) Heatmap of bacterial mcfDNA mapped to genus-level bacterial taxonomy in patient plasma samples (n = 71 patients with 142 samples; 99 healthy control subjects with 99 unique samples). Each column is a plasma sample; each row is a genus. For this analysis, taxa shown are those present in >10 samples with >200 MPM and aggregated at the genus level. (B) Quantification of top differentially abundant taxa (genus). Each point represents a blood sample. (C) Correlation of total MPM with conditioning intensity. (D) Correlation of total MPM with the presence of oropharyngeal mucositis (no comparisons were statistically significant). Nonparametric (Wilcoxon) testing was used throughout (∗∗∗∗P <.0001; ∗∗∗P 0.0001-0.001; ∗∗P = .001-0.01; ∗P = .05-0.01). HC, healthy control; ns, not significant.