ARID1B deficiency affects chromatin structure less notably compared with loss of ARID1A. (A) Venn diagram shows number of distinct and overlapping ATAC-seq peaks lost in Arid1a-KO and Arid1b-KO cells. (B) Fold change (WT vs KO) in normalized read counts for ATAC-seq peaks significantly lost in both Arid1a-KO and Arid1b-KO cells. (C-D) Box plots depict fold change (WT vs KO) in normalized signal values for ATAC-seq peaks significantly lost exclusively in either (C) Arid1a-KO cells or (D) Arid1b-KO cells. Statistical significance was calculated using Wilcoxon rank-sum test.