A Manhattan plot showing the results of the genome-wide association study of predicted platelet reactivity. Each dot corresponds to an included genetic variant: the position on the x-axis indicates the chromosome number and genomic position of the variant, and the position on the y-axis indicates −log₁₀ of the P value of the variant. The horizontal dashed line corresponds to the genome-wide significance threshold. The gene names indicate the protein-coding gene that is nearest to each of these associations. Regions associated with a platelet reactivity phenotype by a previous genome-wide association study are shown in bold. See Figure 2 in the article by Verdier et al that begins on page 1895 for further details.¹