CD45-ADC and HSCT reducces aortic root plaque burden in clonal hematopoiesis driven atherosclerosis. (A) Oil-red-O images of aortic roots, 6 weeks after CD45-ADC treatment, and CD45.1⁺ HSCT in Ldlr KO mice with either WT or Tet2 KO bone marrow. Dashed lines outline atherosclerotic plaque surface area. Scale bar, 200 μm. (B) Quantification of aortic root atherosclerotic lesion surface area, 6 weeks after CD45-ADC treatment, and CD45.1⁺ HSCT in Ldlr KO mice with either WT or Tet2 KO bone marrow.