Group A at baseline represented respondents reporting symptoms and disease history consistent with mild SCD severity. Group A at “worsened” state was asked to assume having chronic pain for 6 months, ≥5 hospital visits to handle pain crises, and a transient ischemic attack (mini stroke). Group B at baseline represented respondents reporting symptoms and disease history consistent with moderate or severe SCD severity. Group B at “worsened” state was asked to assume having: (1) chronic pain for 6 months, ≥5 hospital visits to handle pain crises, and a transient ischemic attack (stroke) if they never had a stroke or ACS; or (2) chronic pain for 6 months, ≥5 hospital visits to handle pain crises, and a debilitating stroke with long-term sequelae if they had a stroke or ACS in the past. Of the 109 respondents, 56 and 53 respondents were in group A and group B, respectively. Error bars indicate 95% CIs.