Figure 7.
![Complement and NETs are increased and correlated with each other in plasma samples from human patients with TRALI. (A) C5a levels (patient with TRALI [TP]: n = 53; healthy control [HC]: n = 30), (B) C1q-C4 complex levels (TP: n = 46; HC: n = 25), and (C) NET formation (MPO DNA; TP: n = 53; HC: n = 30). C5a and NET levels are positively correlated to each other in (D) TPs (n = 53) but not in (E) HCs (n = 30). Data are shown as means ± SD. Statistical analyses were performed with a Mann Whitney U test for panels A-C and a Pearson correlation for panels D-E; ∗P < .05; ∗∗∗P < .001. OD, optical density.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/143/1/10.1182_blood.2023020484/4/blood_bld-2023-020484-gr7.jpeg?Expires=1743018087&Signature=3CMIYqSD4~SkymDglThlGEKPrW4TKNX8avTdHpA9FWtelZM1GJukH5MbYjVlxcykF7sXFMrxkvNTsRROyD5Y5p62HyUedGu8FNhLci3MLtqS4yAqPXBPAaveB0AfR6dvzfPvdjNv26aMbmLwQv1CODyawdJ5EIfzECn9iez8Yq4C8z~M5jfsA-2dVA8~I6VcILD6VV1UnzNqBzF-CE9iKtsir7jmKv30s8-mYIpG7EsOTcERJG6rG47stUmRU9KlSzwLdqYwDIp5qWvFJ9lHfX3ZFheD7XSzh-VS0yHLh21uB3ykr82AL7xmiqyqGT9QtnIi~GlEAzCbpIiujfN47g__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Complement and NETs are increased and correlated with each other in plasma samples from human patients with TRALI. (A) C5a levels (patient with TRALI [TP]: n = 53; healthy control [HC]: n = 30), (B) C1q-C4 complex levels (TP: n = 46; HC: n = 25), and (C) NET formation (MPO DNA; TP: n = 53; HC: n = 30). C5a and NET levels are positively correlated to each other in (D) TPs (n = 53) but not in (E) HCs (n = 30). Data are shown as means ± SD. Statistical analyses were performed with a Mann Whitney U test for panels A-C and a Pearson correlation for panels D-E; ∗P < .05; ∗∗∗P < .001. OD, optical density.
