OEF changes from before to after transplant and compared with healthy controls. (A) OEF does not significantly change in adults with SCD before and after HSCT (P = .28). Individual participant changes are shown overlayed on the symbol and line graph, whereas group data are shown in violin plots, with the bolded dashed line showing the median and smaller dashed lines showing the upper and lower quartiles for participants before (blue plot) and after transplant (green plot). (B) Box-and-whisker plots of OEF shown in healthy adults (left; red dots) and in adults with SCD before transplant (middle; blue dots) and after transplant (right; green dots). OEF in patients with SCD is similar to values found in healthy adults both before (P = .13) and after transplant (P = .34).