Figure 3.
Myeloid FVII deficiency and PAR2 cleavage insensitivity regulate circulating inflammatory monocytes. (A) Flow cytometry analysis of whole lung cell suspension after Poly(I:C) treatment of F7flflLysMcre compared with that of F7flfl littermate control mice. (B) Flow cytometry gating strategy of blood samples pregated on viable, single CD45+ cells. (C) Monocytes in blood after intranasal Poly(I:C) treatment of F7flflLysMcre and F7flfl littermate control mice or (D) F2rl1R38E and WT mice analyzed by flow cytometry. Mean ± SD; the unpaired Student t test ∗P < .05; ∗∗P < .01.