Immune reconstitution and donor engraftment is similar in patients receiving T-reg graft with or without single-agent prophylaxis. (A) Time to neutrophil (≥500/μL) and platelet recovery (≥ 20 × 10³/μL) in patients who received transplant with T-reg graft alone (n = 12) or T-reg graft with single-agent prophylaxis (n = 12). (B) Donor whole-blood, CD15⁺ myeloid, and CD3⁺ T-cell chimerism on day 90 after transplant in patients who received transplant with T-reg graft alone (n = 10) or T-reg graft with single-agent prophylaxis (n = 11). (C) Reconstitution of white blood cell (WBC) count, CD3⁺ T-cell count, and CD19⁺ B-cell count after transplantation in patients who received transplant with T-reg graft alone (n = 11) or T-reg graft with single-agent prophylaxis (n = 12). (D) Reconstitution of total CD4⁺ T-cell count and CD4⁺CD25⁺CD127^lo Treg cell count, and CD4⁺ T-cell–to–Treg ratio after transplantation in patients who received transplant with T-reg graft alone (n = 12) or T-reg graft with single-agent prophylaxis (n = 12). Colored lines represent linear fits of each data set. ANC, absolute neutrophil count; ns, not significant.