Occurrence of bleeds. Twenty-three of 33 patients in the modified full analysis set experienced 173 BEs (excluding menstrual bleeds) during Wilate prophylaxis in WIL-31. All 33 patients experienced a total of 593 BEs during on-demand treatment in WIL-29. (A) Number of BEs by site, type, and severity, (B) Percentage of BEs by site, type, and severity.