Figure 2.
Comparative analysis of BM or peripheral blood immune cell subsets across 5 groups using routine blood tests and cell morphology assays of BM smears. (A) Total number of WBC, granulocytes, monocytes, and lymphocytes in the peripheral blood. (B) Absolute numbers of granulocytes (neutrophils, eosinophils, and basophils) in the peripheral blood. The brown line in neutrophil indicates the cut-off value of 1.5 × 109 cells per L of neutropenia. (C) Proportion of granulocytes, monocytes, and lymphocytes in BM. (D) Proportion of specific granulocyte types (neutrophils, eosinophils, and basophils) in BM. (E-G) Proportions of BM neutrophilic (E-F) and eosinophilic (E,G) lineage cells at different developmental stages for each patient group. ∗P < .05; ∗∗P < .01; ∗∗∗P < .001; ∗∗∗∗P < .0001. Kruskal-Wallis test was used for comparison among 5 groups. Bars represent means ± standard deviation [SD]. The gray area indicates reference range of each index, as described in the Methods section.