IBLS bleeding scale scores at baseline, LTE entry (cycle 1, day 1), LTE 3 months (cycle 4, day 1), LTE 6 months (cycle 7, day 1), and LTE end of study. Bleeding symptoms were grouped by a total of 11 specific sites of bleeding and scored as 0, none; 1, 1 to 5 bruises and/or scattered petechiae; and 2, ≥5 bruises with size >2 cm and/or diffuse petechiae.²⁹ The overall average (SD) score is calculated from the arithmetic mean of 11 site-specific grades. If ≥1 site was missing, the average of the nonmissing sites was used. IBLS, ITP Bleeding Scale.