Figure 3.
Absolute counts and percentages of lymphocytes and monocytes in LK and in PB at the time of leukapheresis are different in RE and NR. (A) ALC in LK of RE = 51 and NR = 44 at day 90 after CAR T-cell infusion. (B) AMC in LK of RE and NR. (C) ALC/AMC ratio in LK of RE and NR. (D) Percentage of lymphocytes in LK of RE and NR. (E) Percentage of monocytes in LK of RE and NR. (F) Lymphocytes/monocytes (%) ratio in LK of RE and NR. (G) ALC in PB at the time of LK (PB) of RE and NR. (H) AMC in PB of RE and NR. (I) ALC/AMC ratio in PB of RE and NR. (J) Percentage of lymphocytes in PB of RE and NR. (K) Percentage of monocytes in PB of RE and NR. (L) Lymphocytes/monocytes (%) ratio in PB of RE and NR. In panels A-L, data of 95 patients were analyzed. In panels A-L, data refer to peripheral absolute blood count the day of LK or absolute cell count in LK products, exact median values are reported. P values were calculated applying the Mann-Whitney test. ns, not significant; ∗P < .05; ∗∗P < .01; ∗∗∗P < .001. ALC, absolute lymphocyte count; LK, leukapheresis products; NR, nonresponders; RE, responders.

Absolute counts and percentages of lymphocytes and monocytes in LK and in PB at the time of leukapheresis are different in RE and NR. (A) ALC in LK of RE = 51 and NR = 44 at day 90 after CAR T-cell infusion. (B) AMC in LK of RE and NR. (C) ALC/AMC ratio in LK of RE and NR. (D) Percentage of lymphocytes in LK of RE and NR. (E) Percentage of monocytes in LK of RE and NR. (F) Lymphocytes/monocytes (%) ratio in LK of RE and NR. (G) ALC in PB at the time of LK (PB) of RE and NR. (H) AMC in PB of RE and NR. (I) ALC/AMC ratio in PB of RE and NR. (J) Percentage of lymphocytes in PB of RE and NR. (K) Percentage of monocytes in PB of RE and NR. (L) Lymphocytes/monocytes (%) ratio in PB of RE and NR. In panels A-L, data of 95 patients were analyzed. In panels A-L, data refer to peripheral absolute blood count the day of LK or absolute cell count in LK products, exact median values are reported. P values were calculated applying the Mann-Whitney test. ns, not significant; ∗P < .05; ∗∗P < .01; ∗∗∗P < .001. ALC, absolute lymphocyte count; LK, leukapheresis products; NR, nonresponders; RE, responders.

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