Significant metabolomics changes in the first week after FMT. Metabolomics changes in (A) carbohydrates, (B) tryptophan metabolites, and (C) short-chain fatty acids between baseline and day 7 after FMT administration among matched CR and non-CR participants, indicated by green and orange lines, respectively. Black bar indicates median values for the metabolite within a group. All unadjusted P values were derived using Wilcox signed rank test.