Figure 5.
Effect of ECP therapy on surface protein expression of CAR-T cells. (A) Surface markers expression intensity in t-SNE plot. (B) MFI of CAR expression on CAR-T cells with/without ECP treatment. (C) Effect of ECP therapy on the expression intensity of surface markers on CAR-T cells. (D) Effect of ECP therapy on the expression intensity of CD95 on effector (CCR7-CD45RA+), naive (CCR7+CD45RA+), central memory (CCR7+CD45RA-), and effector memory (CCR7-CD45RA-) of CD4+ and CD8+CAR-T cells. Samples of 4 individual donors were tested. ∗P < .05.

Effect of ECP therapy on surface protein expression of CAR-T cells. (A) Surface markers expression intensity in t-SNE plot. (B) MFI of CAR expression on CAR-T cells with/without ECP treatment. (C) Effect of ECP therapy on the expression intensity of surface markers on CAR-T cells. (D) Effect of ECP therapy on the expression intensity of CD95 on effector (CCR7-CD45RA+), naive (CCR7+CD45RA+), central memory (CCR7+CD45RA-), and effector memory (CCR7-CD45RA-) of CD4+ and CD8+CAR-T cells. Samples of 4 individual donors were tested. ∗P < .05.

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